Research Scientist TME Tumor Assays, ODDU

Company: Takeda Pharmaceutical
Location: Boston
Posted on: October 30, 2024

Job Description:

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's and . I further attest that all information I submit in my employment application is true to the best of my knowledge.Job DescriptionAbout the role:At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.Join Takeda as a Research Scientist TME Tumor Assays, ODDU -where you will contribute to pre-clinical projects. You will also make contributions from the lab to advance novel and differentiated therapeutic modalities towards preclinical and clinical milestones. As part of the Oncology Drug Discovery Unit (ODDU), you will report to Associate Director, reporting into the Tumor Biology Lab Head within the group.How you will contribute:

• Contribute to pre-clinical projects by designing and developing well-defined mechanistic experiments and projects within Oncology and immuno-oncology research.
• Independently plans new experimental approaches to specific problems/scientific projects using scientific theory and technical literature with flexibility to troubleshoot and change experimental design when necessary.
• Interpret results of complex experiments and documents results according to company policies in electronic lab notebook.
• Analysis, interpretation, and presentation of data to key stakeholders, and play an active role in the subsequent scientific discussions leading to key decisions and program-enabling next steps
• Initiate investigation of new experimental approaches to specific problems using scientific theories, data from internal/external partners, and technical literature
• Work with cultured cell lines and primary cells from multiple species (murine, human) using sterile technique to perform assay development, model characterization, and screening.
• Provide extensive hands-on support for basic molecular biology assays, including but not limited in cell based genetic engineering (CRISPR and other relevant tools), western blotting, qRT-PCR/digital PCR, molecular cloning and lenti-virus package and infection.Minimum Requirements/Qualifications:
  • PhD degree in a scientific discipline, or MS with 4+ years experience, or BS with 6+ years experience
  • Industry experience is preferred, but not required
  • Proven records by leveraging molecular/genetic tools for oncology research and mechanistic investigation
  • Proficiency with common software for documentation and presentation of results at different levels of granularity and documentation in electronic lab notebook.
  • Demonstrate scientific leadership from the lab within project teams.
  • Experience in complicate tumor assay model development.
  • CRISPR based genetic screen experience is preferred
  • Excellent analytical, organizational, interpersonal and time management skills
  • Strong team player who thrives in a dynamic, 'biotech-like' environment.
  • Takeda's high-engagement and ONE Research DEI culture is an important factor in our success; we seek team members who will contribute to and further strengthen that culture in all ways of working.
  • Right attitude (agile, curious, positive, open-minded, "can-do" mindset), must be willing and able to be "hands on," results-oriented mindset.More about us:At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.#LI-SB1Takeda Compensation and Benefits SummaryWe understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. -For Location:Boston, MAU.S. Base Salary Range:$108,500.00 - $170,500.00The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.---The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. -U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. -EEO StatementTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.LocationsBoston, MAWorker TypeEmployeeWorker Sub-TypeRegularTime TypeFull time

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